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Respiratory infections

Respiratory infections: Greek researchers are dealing with this serious problem

18 May, 2023

The largest group worldwide was formed by Greeks who aim to investigate the mechanisms of immune damage in patients with severe pneumonia. The team is financed with 4,7 million Euros by the General Secretariat of Research and Innovation.

Aristidis Iliopoulos, one of the scientific leaders of the project and Professor of Biology and Genetics, Director of the Biology Laboratory at the Medical School of Athens, spoke to APE-MPE and stated that pneumonia is the first cause of death from infectious causes all over the world.

A serious complication of pneumonia are lung infections from fungi and other opportunistic pathogens, as secondary infections that occur e.g. in hospitalized patients with severe pneumonia, from flu or coronavirus, or in immunosuppressed hematological patients.

However, the mechanisms that cause these infections are not known.

As Mr. Iliopoulos states: "With the funding of the General Secretariat of Research and Innovation, Greek scientists will be called upon to solve the riddle of serious respiratory infections and their complications."

Their forces are joined by more than 70 researchers, from the National and Kapodistrian University of Athens (EKPA), the University of Crete and the research institutes Al. Fleming and the Hellenic Pasteur Institute, to create "the largest disease study group in the world, a truly emblematic research effort!"

The purpose of the research is to map the mechanisms that cause the immune damage in patients with severe pneumonia, using the latest technologies in both genetics and biology. The goal is the development of personalized biomarkers and innovative models for the prognosis and prevention of complications.

The research will have a duration of 2 years and in their context, epidemiological and pharmacogenetic studies will take place in patients for the application of antimicrobial treatments.

Biological samples, molecular, immunological, microbiological and clinical data will create an important collection that will help to develop further studies.

 

 The coordinator of the project is the rector of the EKPA, Professor Meletios Athanasios Dimopoulos, and the scientific managers are Mr. Aristides Iliopoulos, Professor of Biology & Genetics and Director of the Biology Laboratory at the Medical School of the EKPA, and Mr. Giorgos Hamilos, Professor of Microbiology at the Medical School of University of Crete.

With information from RES-ICU

source  https://www.real.gr

photo kalhh / https://pixabay.com

 

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